Analysis of the algorithm: From rankings to backup genes.

Ranking section

For each of the affected genes present in the list, a ranking with the score and percentile of every possible gene was obtained. Once this was done, the position for every known backup gene was obtained and the statistical descriptor of all the values calculated.

Table 1. Backup position values for every kernel and net before integration.

Net Kernel Elements Min Max Average Standard_Deviation
cellular_component ct 24 0.0 0.877 0.161 0.232
cellular_component el 24 0.057 0.972 0.554 0.275
cellular_component ka 24 0.0 0.881 0.166 0.236
cellular_component rf 24 0.0 0.867 0.16 0.231
molecular_function ct 24 0.0 0.994 0.276 0.335
molecular_function el 24 0.014 0.987 0.448 0.272
molecular_function ka 24 0.0 0.973 0.269 0.335
molecular_function rf 24 0.0 0.994 0.273 0.336

Table 2. Backup position values for every kernel after integration

Integration Kernel Elements Min Max Average Standard_Deviation
integration_mean_by_presence ct 2 0.065 0.911 0.488 0.423
integration_mean_by_presence el 2 0.118 0.426 0.272 0.154
integration_mean_by_presence ka 2 0.142 0.154 0.148 0.006
integration_mean_by_presence rf 2 0.059 0.515 0.287 0.228
mean ct 2 0.065 0.923 0.494 0.429
mean el 2 0.053 0.343 0.198 0.145
mean ka 2 0.047 0.314 0.18 0.133
mean rf 2 0.047 0.402 0.225 0.178